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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCD
All Species:
14.55
Human Site:
S341
Identified Species:
24.62
UniProt:
Q05655
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05655
NP_006245.2
676
77505
S341
Y
G
K
I
W
E
G
S
S
K
C
N
I
N
N
Chimpanzee
Pan troglodytes
XP_001147999
706
81847
I344
G
K
R
E
P
Q
G
I
S
W
E
S
P
L
D
Rhesus Macaque
Macaca mulatta
XP_001083320
1140
127261
S805
Y
G
K
I
W
E
G
S
S
K
C
N
I
N
N
Dog
Lupus familis
XP_849292
706
81555
I344
G
K
K
E
P
Q
G
I
S
W
E
S
P
L
D
Cat
Felis silvestris
Mouse
Mus musculus
P28867
674
77529
S339
Y
G
K
I
W
E
G
S
T
R
C
T
L
E
N
Rat
Rattus norvegicus
P09215
673
77502
S339
Y
G
K
I
W
E
G
S
N
R
C
R
L
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509836
708
81415
E365
P
E
I
A
P
E
P
E
S
D
I
A
P
P
S
Chicken
Gallus gallus
NP_001006133
699
80179
T339
D
K
L
W
E
G
S
T
A
K
A
A
P
R
I
Frog
Xenopus laevis
NP_001084460
683
78181
T340
D
K
L
W
E
G
I
T
P
H
P
H
I
S
L
Zebra Danio
Brachydanio rerio
Q90XF2
588
67303
V276
E
R
I
Y
A
M
K
V
V
K
K
E
L
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P83099
671
76314
A327
Q
K
S
G
R
F
T
A
P
A
T
V
I
P
R
Honey Bee
Apis mellifera
XP_394743
624
71014
P286
F
P
S
G
R
I
T
P
P
A
T
N
L
P
R
Nematode Worm
Caenorhab. elegans
P34722
704
80280
V367
W
G
G
G
D
G
P
V
K
K
F
A
L
P
H
Sea Urchin
Strong. purpuratus
XP_787505
585
66691
E279
F
G
K
V
M
L
A
E
Q
K
G
T
K
K
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.7
58.5
63.5
N.A.
90.3
89.5
N.A.
63.7
82.4
81.4
33.2
N.A.
46.7
45.2
47.1
49.1
Protein Similarity:
100
76.7
59
77.6
N.A.
95.4
95.2
N.A.
77.9
89.9
89.5
50.8
N.A.
61.9
61.3
64.7
63.6
P-Site Identity:
100
13.3
100
20
N.A.
66.6
66.6
N.A.
13.3
6.6
6.6
13.3
N.A.
6.6
6.6
13.3
20
P-Site Similarity:
100
40
100
40
N.A.
86.6
86.6
N.A.
20
20
26.6
20
N.A.
13.3
20
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
8
8
8
15
8
22
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
29
0
0
0
0
% C
% Asp:
15
0
0
0
8
0
0
0
0
8
0
0
0
0
15
% D
% Glu:
8
8
0
15
15
36
0
15
0
0
15
8
0
15
0
% E
% Phe:
15
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% F
% Gly:
15
43
8
22
0
22
43
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
8
% H
% Ile:
0
0
15
29
0
8
8
15
0
0
8
0
29
0
8
% I
% Lys:
0
36
43
0
0
0
8
0
8
43
8
0
8
8
0
% K
% Leu:
0
0
15
0
0
8
0
0
0
0
0
0
36
15
8
% L
% Met:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
22
0
15
36
% N
% Pro:
8
8
0
0
22
0
15
8
22
0
8
0
29
29
0
% P
% Gln:
8
0
0
0
0
15
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
8
8
0
15
0
0
0
0
15
0
8
0
8
15
% R
% Ser:
0
0
15
0
0
0
8
29
36
0
0
15
0
8
8
% S
% Thr:
0
0
0
0
0
0
15
15
8
0
15
15
0
0
0
% T
% Val:
0
0
0
8
0
0
0
15
8
0
0
8
0
8
0
% V
% Trp:
8
0
0
15
29
0
0
0
0
15
0
0
0
0
0
% W
% Tyr:
29
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _